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Pan-histone deacetylase (HDAC) inhibitor panobinostat depletes CXCR4 levels and signaling and exerts synergistic anti-myeloid activity in combination with CXCR4 antagonists.
Stromal cell derived factor-1 (SDF-1 or CXCL12) and its receptor CXCR4 are ...
Mandawat A, Fiskus W, Buckley KM, Robbins K, Rao R, Balusu R, Navenot JM, Wang ZX, Ustun C, Chong DG, Atadja P, Fujii N, Peiper SC, Bhalla K,
http://dx.doi.org/10.1182/blood-2010-05-284414
Blood. 2010 Sep 1.
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Serum Lipoprotein-Associated Phospholipase A(2) and C-Reactive Protein Levels in Association Between Periodontal Disase and Hyperlipidemia.
Background: The aim of this study was to evaluate serum ...
Fentoglu O, Koroglu BK, Kara Y, Dogan B, Yilmaz G, Sutcu R, Ay ZY, Tonguc MO, Orhan H, Tamer MN, Kirzioglu FY,
http://dx.doi.org/10.1902/jop.2010.100417
J Periodontol. 2010 Sep 1.
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Peptide-binding sites as revealed by the crystal structures of the human Hsp40 Hdj1 C-terminal domain in complex with the octapeptide from human Hsp70.
Heat shock protein (Hsp) 40s play essential roles in cellular processes by ...
Suzuki H, Noguchi S, Arakawa H, Tokida T, Hashimoto M, Satow Y,
http://dx.doi.org/10.1021/bi100876n
Biochemistry. 2010 Sep 1.
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Cardioprotective effect of zinc requires ErbB2 and Akt during hypoxia/reoxygenation.
Recent literature suggests that exogenous zinc can prevent ischemia ...
Viswanath K, Bodiga S, Balogun V, Zhang A, Bodiga VL,
http://dx.doi.org/10.1007/s10534-010-9371-8
Biometals. 2010 Aug 31.
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Binding of protein kinase inhibitors to synapsin I inferred from pair-wise binding site similarity measurements.
Predicting off-targets by computational methods is getting increasing ...
De Franchi E, Schalon C, Messa M, Onofri F, Benfenati F, Rognan D,
http://dx.doi.org/10.1371/journal.pone.0012214
PLoS One. 2010 Aug 16;5(8). pii: e12214.
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