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Latest Publications on P53
Piwil2 suppresses p53 by inducing phosphorylation of signal transducer and activator of transcription 3 in tumor cells.
Piwi proteins have been implicated in germ cell proliferation, ...
Lu Y, Zhang K, Li C, Yao Y, Tao D, Liu Y, Zhang S, Ma Y,
http://dx.doi.org/10.1371/journal.pone.0030999
PLoS One. 2012;7(1):e30999. Epub 2012 Jan 27.

Effect of maternal and post-weaning folate supply on gene-specific DNA methylation in the small intestine of weaning and adult apc and wild type mice.
Increasing evidence supports the developmental origins of adult health and ...
McKay JA, Williams EA, Mathers JC,
http://dx.doi.org/10.3389/fgene.2011.00023
Front Genet. 2011;2:23. Epub 2011 May 23.

Clinicopathological significance of cathepsin D expression in non-small cell lung cancer is conditional on apoptosis-associated protein phenotype: an immunohistochemistry study.
Cathepsin D is a well-known peptidase which belongs to the family of ...
Fan C, Lin X, Wang E,
http://dx.doi.org/10.1007/s13277-012-0338-y
Tumour Biol. 2012 Feb 3.

Pharmacokinetics and tissue and tumor exposure of CP-31398, a p53-stabilizing agent, in rats.
PURPOSE: CP-31398 ...
Kapetanovic IM, Muzzio M, McCormick DL, Thompson TN, Johnson WD, Horn TL, Mohammed A, Rao CV, Kopelovich L,
http://dx.doi.org/10.1007/s00280-011-1811-9
Cancer Chemother Pharmacol. 2012 Feb 3.

The Aurora kinase A inhibitor MLN8237 Enhances Cisplatin-induced Cell Death in Esophageal Adenocarcinoma Cells.
Esophageal adenocarcinomas (EACs) are poorly responsive to ...
Sehdev V, Peng D, Soutto M, Washington MK, Revetta F, Ecsedy JA, Zaika AI, Rau T, Schneider-Stock R, Belkhiri A, El-Rifai W,
http://dx.doi.org/10.1158/1535-7163.MCT-11-0623
Mol Cancer Ther. 2012 Feb 1.

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05/Feb/2012:14:20:57