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Mdm2 inhibition induces apoptosis in p53 deficient human colon cancer cells by activating p73- and E2F1-mediated expression of PUMA and Siva-1.
Camptothecin (CPT) and Nutlin-3 caused apoptosis by increasing p53 protein ...
Ray RM, Bhattacharya S, Johnson LR,
http://dx.doi.org/10.1007/s10495-010-0538-0
Apoptosis. 2010 Sep 2.
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Comparison of p53 and Epidermal Growth Factor Receptor Gene Status Between Primary Tumors and Lymph Node Metastases in Non-Small Cell Lung Cancers.
BACKGROUND: To obtain insight into the cancer progression and metastatic ...
Chang YL, Wu CT, Shih JY, Lee YC,
http://dx.doi.org/10.1245/s10434-010-1295-6
Ann Surg Oncol. 2010 Sep 2.
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Effect of rapamycin, an mTOR inhibitor, on radiation sensitivity of lung cancer cells having different p53 gene status.
Activation to a large extent of the phosphatidylinositol 3-kinase ...
Nagata Y, Takahashi A, Ohnishi K, Ota I, Ohnishi T, Tojo T, Taniguchi S,
Int J Oncol. 2010 Oct;37(4):1001-10.
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Inhibitory effects of docosyl p-coumarate on DNA topoisomerase activity and human cancer cell growth.
We previously found six compounds of alkyl p-coumarates from a composite ...
Mizushina Y, Nishimura K, Takenaka Y, Takeuchi T, Sugawara F, Yoshida H, Tanahashi T,
Int J Oncol. 2010 Oct;37(4):993-1000.
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Biological effects of induced MYCN hyper-expression in MYCN-amplified neuroblastomas.
Neuroblastoma is a childhood malignancy of the sympathetic nervous system. ...
Torres J, Regan PL, Edo R, Leonhardt P, Jeng EI, Rappaport EF, Ikegaki N, Tang XX,
Int J Oncol. 2010 Oct;37(4):983-91.
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