Biojournals.com Latest GPCR Publications http://www.biojournals.com/GPCR.html Latest publications on GPCR en-us biojournals@sci7.com hourly 1 2000-01-01T12:00+00:00 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=19013155 Adenosine A(2A) receptors assemble into higher-order oligomers at the plasma membrane. Oligomerization of G protein-coupled receptors (GPCRs) is known to play ... http://dx.doi.org/10.1016/j.febslet.2008.09.062 FEBS Lett. 2008 Nov 11. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=19012575 Quantitative structure activity relationship and pharmacophore studies of adenosine receptor a inhibitors. Adenosine receptor A2B (ADoR A2B) is an important G protein-coupled ... http://dx.doi.org/10.1111/j.1747-0285.2008.00714.x Chem Biol Drug Des. 2008 Nov;72(5):395-408. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=19012393 Assessment of Additive/Nonadditive Effects in Structure-Activity Relationships: Implications for Iterative Drug Design. Free-Wilson (FW) analysis is common practice in medicinal chemistry and is ... http://dx.doi.org/10.1021/jm801070q J Med Chem. 2008 Nov 14. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=19010788 The C-terminal tail of CRTH2 is a key molecular determinant that constrains GalphaI- and downstream-signaling cascade activation. Prostaglandin D(2) activation of the seven transmembrane receptor CRTH2 ... http://dx.doi.org/10.1074/jbc.M806867200 J Biol Chem. 2008 Nov 14. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=19010327 Liver Myofibroblasts Regulate Infiltration and Positioning of Lymphocytes in Human Liver. BACKGROUND & AIMS: The recruitment of lymphocytes to tissues via ... http://dx.doi.org/10.1053/j.gastro.2008.10.020 Gastroenterology. 2008 Oct 15. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=19008402 A short amino acid sequence containing tyrosine in the N-terminal region of G protein-coupled receptors is critical for their potential use as co-receptors for human and simian immunodeficiency viruses. Various G protein-coupled receptors (GPCRs) have the potential to work as ... http://dx.doi.org/10.1099/vir.0.2008/002188-0 J Gen Virol. 2008 Dec;89(Pt 12):3126-36. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=19008357 The G-protein-coupled receptor kinase 5 inhibits NF{kappa}B transcriptional activity by inducing nuclear accumulation of I{kappa}B{alpha} G-protein-coupled receptor (GPCR) kinases, GRKs, are known as ... http://dx.doi.org/10.1073/pnas.0804446105 Proc Natl Acad Sci U S A. 2008 Nov 13. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=19007813 Rapid, semi-automated, and inexpensive radioimmunoassay of cAMP: Application in GPCR-mediated adenylate cyclase assays. Cyclic AMP (cAMP) is an important signal transduction second messenger ... http://dx.doi.org/10.1016/j.jneumeth.2008.10.016 J Neurosci Methods. 2008 Oct 21. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=19005063 G-protein-coupled receptor screen reveals a role for chemokine receptor CCR5 in suppressing microglial neurotoxicity. G-protein-coupled receptors (GPCRs) form the largest superfamily of ... http://dx.doi.org/10.1523/JNEUROSCI.2920-08.2008 J Neurosci. 2008 Nov 12;28(46):11980-8. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=19004627 Insights from biophysical studies on the role of polyunsaturated fatty acids for function of G-protein coupled membrane receptors. The composition of the lipid matrix is critical for function of membrane ... http://dx.doi.org/10.1016/j.plefa.2008.09.002 Prostaglandins Leukot Essent Fatty Acids. 2008 Nov 10. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=19001361 Engineered protein connectivity to actin mimics PDZ-dependent recycling of GPCRS but not its regulation by HRS. Many G protein-coupled receptors (GPCRs) recycle after agonist-induced ... http://dx.doi.org/10.1074/jbc.M806370200 J Biol Chem. 2008 Nov 10. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=19001095 Identification of G-protein {alpha} subunit palmitoylating enzyme. Heterotrimeric G-protein alpha subunit (Galpha) is targeted to the ... http://dx.doi.org/10.1128/MCB.01144-08 Mol Cell Biol. 2008 Nov 10. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=19001067 Functional Selectivity of GPCR Ligand Stereoisomers: New Pharmacological Opportunities (Relates to article by Woo et al., Fast Forward 10 Nov 08). It is now well established that any given ligand for a G-protein coupled ... http://dx.doi.org/10.1124/mol.108.052944 Mol Pharmacol. 2008 Nov 10. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=19001049 An energy supply network of nutrient absorption coordinated by calcium and T1R taste receptors in rat small intestine. T1R taste receptors are present throughout the gastrointestinal tract. ... http://dx.doi.org/10.1113/jphysiol.2008.159616 J Physiol. 2008 Nov 10. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=19000738 Accessory proteins are vital for the functional expression of certain G protein-coupled receptors. Certain G protein-coupled receptors (GPCRs) fail to be expressed in a ... http://dx.doi.org/10.1016/j.mce.2008.10.004 Mol Cell Endocrinol. 2008 Oct 19.