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Latest Publications on Drosophila Model System
Lysosomal dysfunction promotes cleavage and neurotoxicity of tau in vivo.
Expansion of the lysosomal system, including cathepsin D upregulation, is ...
Khurana V, Elson-Schwab I, Fulga TA, Sharp KA, Loewen CA, Mulkearns E, Tyynela J, Scherzer CR, Feany MB,
http://dx.doi.org/10.1371/journal.pgen.1001026
PLoS Genet. 2010 Jul 15;6(7):e1001026.

Histone Deacetylase Rpd3 Regulates Olfactory Projection Neuron Dendrite Targeting via the Transcription Factor Prospero.
Compared to the mechanisms of axon guidance, relatively little is known ...
Tea JS, Chihara T, Luo L,
http://dx.doi.org/10.1523/JNEUROSCI.1643-10.2010
J Neurosci. 2010 Jul 21;30(29):9939-46.

The Planar Polarity Protein Scribble1 Is Essential for Neuronal Plasticity and Brain Function.
Scribble (Scrib) is a key regulator of apicobasal polarity, presynaptic ...
Moreau MM, Piguel N, Papouin T, Koehl M, Durand CM, Rubio ME, Loll F, Richard EM, Mazzocco C, Racca C, Oliet SH, Nora Abrous D, Montcouquiol M, Sans N,
http://dx.doi.org/10.1523/JNEUROSCI.6007-09.2010
J Neurosci. 2010 Jul 21;30(29):9738-9752.

Pseudomonas Exotoxin kills Drosophila S2 cells via Apoptosis.
Pseudomonas exotoxin A (PE) is cytotoxic for eukaryotic cells because it ...
Sharma AK, Fitzgerald D,
http://dx.doi.org/10.1016/j.toxicon.2010.07.007
Toxicon. 2010 Jul 23.

Insights from Drosophila models of Alzheimer's disease.
AD (Alzheimer's disease) is a neurodegenerative disorder characterized by ...
Cowan CM, Shepherd D, Mudher A,
http://dx.doi.org/10.1042/BST0380988
Biochem Soc Trans. 2010 Aug 1;38(4):988-92.

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