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Combination of rapamycin and 17-allylamino-17-demethoxygeldanamycin abrogates Akt activation and potentiates mTOR blockade in breast cancer cells.
Increased Akt phosphorylation was reported in cancer cell lines and tumor ...
Roforth MM, Tan C,
http://dx.doi.org/10.1097/CAD.0b013e3283067681
Anticancer Drugs. 2008 Aug;19(7):681-8.
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Cross-talk between notch and the estrogen receptor in breast cancer suggests novel therapeutic approaches.
High expression of Notch-1 and Jagged-1 mRNA correlates with poor ...
Rizzo P, Miao H, D'Souza G, Osipo C, Yun J, Zhao H, Mascarenhas J, Wyatt D, Antico G, Hao L, Yao K, Rajan P, Hicks C, Siziopikou K, Selvaggi S, Bashir A, Bhandari D, Marchese A, Lendahl U, Qin JZ, Tonetti DA, Albain K, Nickoloff BJ, Miele L,
http://dx.doi.org/10.1158/0008-5472.CAN-07-5744
Cancer Res. 2008 Jul 1;68(13):5226-35.
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The histone demethylase KDM5b/JARID1b plays a role in cell fate decisions by blocking terminal differentiation.
The histone demethylase KDM5b (Lysine (K) demethylase 5b) specifically ...
Dey BK, Stalker L, Schnerch A, Bhatia M, Taylor-Papidimtriou J, Wynder C,
http://dx.doi.org/10.1128/MCB.00128-08
Mol Cell Biol. 2008 Jun 30;.
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P21 and p27: roles in carcinogenesis and drug resistance.
Human cancers arise from an imbalance of cell growth and cell death. Key ...
Abukhdeir AM, Park BH,
http://dx.doi.org/10.1017/S1462399408000744
Expert Rev Mol Med. 2008 Jul 1;10:e19.
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Prospero-related homeobox 1 and liver receptor homolog 1 coordinately regulate long-term proliferation of murine fetal hepatoblasts.
During early to late-fetal liver development, bipotential hepatoblasts ...
Kamiya A, Kakinuma S, Onodera M, Miyajima A, Nakauchi H,
http://dx.doi.org/10.1002/hep.22303
Hepatology. 2008 Feb 25;48(1):252-264.
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