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Molecular basis for cyclooxygenase inhibition by the non-steroidal anti-inflammatory drug, naproxen.
Naproxen ((S)-6-methoxy-alpha-methyl-2-naphthaleneacetic acid) is a ...
Duggan KC, Walters MJ, Musee J, Harp JM, Kiefer JR, Oates JA, Marnett LJ,
http://dx.doi.org/10.1074/jbc.M110.162982
J Biol Chem. 2010 Sep 1.
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The autoimmune TCR-Ob.2F3 can bind to MBP85-99/HLA-DR2 having an unconventional mode as in TCR-Ob.1A12.
The generation of T cell receptor (TCR) sequence diversity can produce ...
Kato Z, Stern JN, Nakamura HK, Miyashita N, Kuwata K, Kondo N, Strominger JL,
http://dx.doi.org/10.1016/j.molimm.2010.07.010
Mol Immunol. 2010 Aug 30.
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Insights into the Mechanism of Ligand Binding to Octopine Dehydrogenase from Pecten maximus by NMR and Crystallography.
Octopine dehydrogenase (OcDH) from the adductor muscle of the great ...
Smits SH, Meyer T, Mueller A, van Os N, Stoldt M, Willbold D, Schmitt L, Grieshaber MK,
http://dx.doi.org/10.1371/journal.pone.0012312
PLoS One. 2010 Aug 19;5(8). pii: e12312.
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Chelation-Assisted, Copper(II)-Acetate-Accelerated Azide-Alkyne Cycloaddition.
We described in a previous communication a variant of the popular ...
Kuang GC, Michaels HA, Simmons JT, Clark RJ, Zhu L,
http://dx.doi.org/10.1021/jo101305m
J Org Chem. 2010 Aug 31.
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Enzymatic Ring-Opening Mechanism of Verdoheme by the Heme Oxygenase: A Combined X-ray Crystallography and QM/MM Study.
The least understood mechanism during heme degradation by the enzyme heme ...
Lai W, Chen H, Matsui T, Omori K, Unno M, Ikeda-Saito M, Shaik S,
http://dx.doi.org/10.1021/ja104674q
J Am Chem Soc. 2010 Aug 31.
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